Acute kidney injury (AKI) is reported in up to 30%1 of patients undergoing cardiac surgery and is a recognized independent predictor of both morbidity and mortality. To date, no preventive strategies have been shown in clinical trials to reduce the occurrence of cardiac surgery-associated AKI.
30% of patients undergoing cardiac surgery suffer from AKI
Leading to higher morbidity and mortality3
RenalGuard demonstrated a 52% reduction in AKI vs. standard of care
- The KIDNEY study is a 220-patient (on-pump) randomized controlled study
- 110 patients in each arm (RenalGuard therapy vs. standard of care).
- Study conducted at a leading hospital in the UK.
- The number needed to treat (NNT) with the RenalGuard system to prevent AKI was 9 patients.
How RenalGuard Prevents AKI in Cardiac Surgery
Automated Fluid Management System
Continuous Diuresis and Balanced Rehydration
Before, During, and After Surgery
Mechanism of Action
- Lannemyr L.Effects of Cardiopulmonary Bypass on Renal Perfusion, Filtration, and Oxygenation in Patients Undergoing Cardiac Surgery. Anesthesiology.
- Bellomo R, Auriemma S, Fabbri A, D’Onofrio A, Katz N, McCullough PA, Ricci Z, Shaw A, Ronco C: The pathophysiology of cardiac surgery-associated acute kidney injury.
- Vives M, Hernandez A, Parramon F, et al. Acute kidney injury after cardiac surgery.